![]() How to use it: Best applied at night to start, and eventually increased to twice daily for maximum effects. To avoid this, apply hydroquinone sparingly to the center of your spot and feather toward the edges. Another potential side effect is “ghosting,” which is the inadvertent lightening of the skin outside of the targeted area. Cook-Bolden, who always recommends trying a spot test first. “As with any product that is applied to the skin, hydroquinone can cause dryness, redness, and burning, which may signal an allergic reaction to the ingredient,” cautions Dr. ![]() However, most should anticipate 8 to 12 weeks of use to see a visible difference depending on a few factors (such as the extent of the hyperpigmentation, how deeply it penetrates, how long it’s been there, etc.). In some cases, the effects of hydroquinone can be seen in as little as two weeks. This extra melanin can be triggered by a lot of different things, she says: “ Hormones-both estrogen and progesterone-can increase the level of melanin-why pregnant women see dark spots that often lighten following birth the sun can increase the level of melanin-why we have more dark spots after the summer and age can increase the size of the melanocytes-why we see dark age spots in older patients.” ![]() “Dark spots or hyperpigmentation are due to the overproduction of melanin in the skin by melanocytes,” plastic surgeon Melissa Doft, MD, tells SELF. Below, we dive into what causes dark spots in the first place, plus nine different dark spot treatments that dermatologists recommend. So, if your ultimate quest is to achieve the no-makeup look, these skin-care products and tips can help. The number one thing that can keep you from the I-don’t-need-makeup type of complexion is uneven skin tone. What ingredients should you look for? And most important, which ones will get rid of dark spots for good? To answer these questions, SELF spoke to several dermatologists to find out how they treat dark spots on the face. Other rarer, more severe side effects included coughing up blood and obstructive pulmonary disease.When it comes to dark spot treatments, there are so many skin-care options out there that it can be hard to know where to start. Side effects include wheezing, rash, nausea, allergic reaction resembling anaphylaxis, decreased blood pressure, vomiting, rapid skin swelling, cramps, and diarrhea. I thought about using glutathione to lighten my age spots, but after reading the list of possible side effects, I put the box back on the store’s shelf quickly. Since they reside inside cells, they have the opportunity to destroy free radicals. Glutathione is the most important antioxidant in the body, because it exists inside the cell. I, too, am dealing with age spots and would like to remove them, so I investigated glutathione. ![]() I look for further information about any product before using it in or on my body. I’m sure an overdose would be reason for fear, but if taken as directed, it should not harm you. June 22, - I wouldn’t be too afraid of glutathione, because it occurs naturally in the body in every one of our cells. It contains 12 antioxidants in all, like collagen, coQ10, NAC, alpha lipoic acid and placenta extract which are very good for skin care, anti-aging and skin lightening.
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